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KMID : 0363420170310010063
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Journal of Korean Oriental Pediatrics
2017 Volume.31 No. 1 p.63 ~ p.73
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The Trend of Clinical Research on Treatment for Precocious Puberty - Focusing on Recent Studies in the Chinese Medical Journal CAJ -
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Kweon Ji-Hyeon
Lee Seung-Yeon
Yu Sun-Ae
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Abstract
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Objectives: The purpose of this study is to analyze recent clinical studies on treatment for precocious puberty.
Methods: 28 clinical studies from January 2009 to December 2016 about precocious puberty from the China Academic
Journal (CAJ), China National Knowledge Infrastructure (CNKI), were selected and reviewed: 22 case control studies and 6 case series.
Results: The main traditional Chinese medicine (TCM) treatment was the herbal decoctions and granules. The frequently
used herbs were root of Bupleurum falcatum (柴胡), fruit of Prunella vulgaris var. aleutica (夏枯草), root stem of Anemarrhena asphodeloides (知母), dried fungus nucleus of Poria cocos (茯?), Rehmannia glutinosa var. purpurea (生地黃), peony Paeonia suffruticosa Andrews (牧丹皮), bark of Phellodendron amurense (黃柏), roots of a plant Paeoniae lactiflora (白芍藥). On the other hand, the main western medicine (WM) for precocious puberty was Gonadotropin-releasing hormone agonist (GnRHa). Total effective rate of the TCM group was 62.96-100%, that of the WM group was 36.6-93.3% and that of the TCM-WM group was 77.8-93.75%.
Conclusions: Traditional Chinese medicine has been shown as an effective treatment for precocious puberty. These research results can be utilized in other clinical studies and in treatment of precocious puberty.
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KEYWORD
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Precocious puberty, Trend of clinical research, Traditional chinese medicine, Chinese medical journal
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